Opportunity Information: Apply for RFA HD 21 023

The NICHD Program Project Grants for HIV Research (P01 Clinical Trial Optional) opportunity (RFA HD 21 023) is a discretionary federal grant offered by the Department of Health and Human Services through the National Institutes of Health. It is designed to fund larger, coordinated research efforts where HIV is the clear and central scientific focus. Rather than supporting a single standalone study, this mechanism is meant for an integrated research program made up of multiple related projects that are intentionally built to reinforce one another. Each project within the program is expected to be strong enough to stand on its own scientifically, but the overall application should make a convincing case that the projects are more powerful and more informative when carried out together as a unified program, creating synergy across the set of studies.

This opportunity uses the Program Project (P01) structure, which typically supports teams of investigators working on a shared theme, with multiple interlocking research aims. The "clinical trial optional" designation means applicants may propose clinical trials if they are appropriate for the research goals, but a clinical trial is not required. The funding activity category is Health, Income Security and Social Services, and the listing is associated with CFDA number 93.865. The source description emphasizes that HIV must be a well-defined central objective, so proposed programs should not treat HIV as a peripheral component; the expectation is that the research questions, design, and program integration all clearly align around HIV-focused aims.

A wide range of applicants are eligible, reflecting NIH's broad eligibility framework for research funding. Eligible applicants include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations (other than federally recognized tribal governments); public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (excluding institutions of higher education when specified); for-profit organizations other than small businesses; small businesses; and other entities as described in the full eligibility instructions referenced in the announcement. This breadth allows academic institutions, governmental bodies, nonprofit research organizations, and certain private-sector entities to compete, as long as the proposed program fits the scientific purpose and meets NIH requirements.

In terms of scale, the opportunity lists an award ceiling of $1,000,000 and anticipates making about two awards. The notice was created on August 17, 2020, and the original closing date was March 31, 2021. Taken together, these details signal a relatively selective competition intended for mature, well-developed program project applications with a clear plan for coordination across projects and a strong justification for why the multi-project approach is necessary to advance HIV research goals.

  • The Department of Health and Human Services, National Institutes of Health in the health, income security and social services sector is offering a public funding opportunity titled "NICHD Program Project Grants for HIV Research (P01 Clinical Trial Optional)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865.
  • This funding opportunity was created on Aug 17, 2020.
  • Applicants must submit their applications by Mar 31, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $1,000,000.00 in funding.
  • The number of recipients for this funding is limited to 2 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for RFA HD 21 023

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